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Chunk #30 — RESULTS — MAOA-LPR: main effects and interaction with stressful life events at ≤ age 3.5 years; influence on hyperactivity — Girls

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Early life stress, MAOA, and gene-environment interactions predict behavioral disinhibition in children.
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In the presence of the interaction there were main effects of MAOA-LPR on hyperactivity in girls at age 4 (β = 0.33; 95% CI: 0.11 to 0.55; p = 0.003) and age 7 (β = 0.29; 95% CI: 0.07 to 0.51; p = 0.01) such that in girls exposed to little or no adversity, the high activity MAOA-LPR allele was associated with greater hyperactivity (Figure 1, B1, B2). There were no main effects of MAOA-LPR independent of the interaction.