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Chunk #47 — Discussion — Gender differences in risk for CD

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Monoamine oxidase A and childhood adversity as risk factors for conduct disorder in females.
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Further analysis of the transmission of antisocial behavior between twins and their parents is required to resolve the role of childhood adversity in the correlation between parental ASP and child CD. Larger samples would enable the characterization of profiles of covariates that differentiate between subjects who have high genetic risk yet did not manifest the disorder. However, the small number of subjects and large number of potential covariates precludes such post-hoc mining of the data for this purpose. It would be helpful to test the assumptions of X-linked inheritance on CD diagnosis to determine whether they explain the lower prevalence of CD in females compared to males.