Summary information of alcohol-related traits and comorbid major depressive disorder by gender is shown in Table 1. In general, men exhibited more severe alcohol-related problems compared to women. Men had younger age-at-onset of AD, drank more to feel the effects of ethanol during both early exposures and the period of heaviest drinking and had more withdrawal symptoms than women (detailed description of alcohol-related behaviors for the whole IASPSAD family sample is in Prescott et al., 2005).
