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Chunk #31 — Discussion — Development of Interregional Functional Connectivity

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Development of large-scale functional brain networks in children.
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We used the parcellation scheme of Mesulam to examine developmental changes in the functional connectivity of five major functional divisions of the human brain. Briefly, the primary sensory division consists of unimodal regions for processing visual, auditory, somatosensory, olfactory, and gustatory signals. The subcortical division includes deep brain nuclei, notably the basal ganglia and thalamus, and the association division comprises higher order multimodal regions, including the lateral prefrontal, parietal, and temporal cortices. The paralimbic division consists of the insula, anterior cingulate cortex, posterior cingulate cortex and the orbitofrontal cortex, and the limbic division includes the amygdala and hippocampus. Together, these divisions map the external world into brains' internal sensory, attentional, mnemonic, emotional, and motivational systems [60].