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Chunk #30 — Discussion — Development of Functional Hierarchical Organization

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Development of large-scale functional brain networks in children.
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vulnerable to attack on hubs [51]. The presence of hierarchical organization in the large-scale brain networks of children and young-adults suggests efficient functional connectivity patterns within these networks at the expense of higher vulnerability to attacks. Lower levels of hierarchical organization in children may therefore be protective to such vulnerability, allowing for more flexibility in network reconfiguration on the basis of individual differences in cognitive experience and reserve. How modularity and hierarchy emerge in functionally meaningful ways is an important topic for future research, but the important finding here is that quantitative measures of hierarchy can be used to examine the emergence of functional hierarchy in the developing brain.