and 6 downregulated) and 216 (79 upregulated and 137 downregulated) DEG in the caudate and nucleus accumbens, respectively (FDR < 0.05; Fig. 1A; Table S2), and none for the OFC (Fig. S3). Examining overlap of DEG sets between global, caudate, and nucleus accumbens identifies 3 DEG (Fig. 1B). There were also 20 DEG in the intersection of the caudate and global gene sets and 177 DEG in the intersection of the nucleus accumbens and global gene sets (Fig. 1B). No overlapping DEGs were detected between the caudate and the nucleus accumbens alone.
