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Chunk #12 — Results — Pairwise associations between brain IDPs and other measures

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Multimodal population brain imaging in the UK Biobank prospective epidemiological study.
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We conducted simple univariate association analyses to illustrate the richness of relationships between IDPs and other available variables, as well as the statistical power afforded by ~5000 subjects. We individually correlated all 2501 brain IDPs with 1100 other Biobank variables, where the latter were broadly grouped into 11 categories (Figs 1-4,6, Supplementary Fig 2). Even after false discovery rate (FDR) multiple comparison correction for these 2.8 million correlations, 57 out of the 66 combinations of brain modalities and non-brain-imaging categories show significant associations. Some variable categories exhibited large numbers of associations with IDPs (e.g., height and weight), whereas others (e.g. cognitive measures and alcohol/tobacco intake) had more focused associations.