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Chunk #31 — Discussion — Strengths and Limitations

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Childhood adversity moderates the effect of ADH1B on risk for alcohol-related phenotypes in Jewish Israeli drinkers.
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GG and parental alcoholism is most likely due to the low rates of alcohol consumption (and related problems) in the parental cohort of older Israelis (Levav et al., 1993). Finally, the interaction results described in this study should be replicated in additional well-powered samples.