The second strategy, eQTL mapping, is used to link SNPs to genes with which these SNPs show a significant eQTL association (i.e., allelic variation at the SNP affects the expression of that gene). This strategy is based on information from 3 data repositories (GTEx, Blood eQTL browser, and BIOS QTL browser), and uses cis-eQTLs, which can map SNPs to genes that lie up to 1 Mb apart. We applied a false discovery rate (FDR) of 0.05 to define significant eQTL associations.
