We performed gene-set analysis for PAU for curated gene sets and Gene Ontology (GO) terms using MAGMA [17, 18]. We then used MAGMA for gene-property analyses to test the relationships between tissue-specific gene expression profiles and PAU-gene associations. We analyzed gene expression data from 53 GTEx (v7) tissues. We also performed gene-set analysis on the 152 prioritized genes using MAGMA. Gene sets with adjusted p-value < 0.05 were considered as significant.
