The second cohort was similar to the original cohort on most background characteristics (Table 1) with the exception that the second cohort reported significantly more drinks per drinking day (p < 0.01), binges per month (p < 0.05), and maximum number of drinks in one drinking occasion within the past six months (p < 0.05). Because these drinking variables were highly intercorrelated (r’s > 0.25, p’s < 0.05), binges per month was selected as a covariate to avoid collinearity and included in the analyses comparing cohorts. Alcohol produced a similar BrAC curve in both cohorts (time × cohort. F(1,4) = 1.84, p = 0.12; Table 1). Acute response to alcohol did not significantly differ by sex in either cohort.