To assess the genetic component contributing to gene expression variability, we estimated intraclass correlation coefficients (ICC) [31] in the 15 samples measured in replicate on 5–6 different plates and 2–3 different days. Between-subject variance accounted for a median of 60% of total probe expression variance (Supplementary Table 4 in Dataset S1; Figure S4). The 746 probes for the top 2,980 cerebellar cisSNP associations had higher between-subject variance (median = 78%).
