Using multivariable linear regression, we next estimated the percent variation in cerebellar probe expression levels due to the “best” cisSNP for each transcript after accounting for technical and biological covariates. We found that the “best” cisSNP explained a median of ∼3% of the expression variation. For the top 746 probes, the “best” cisSNPs accounted for a median of 18% of the expression variance (Table 2, Supplementary Table 5 in Dataset S1).
