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Chunk #18 — Online Methods — Gene-based analysis

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Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.
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SNP-based P-values from the meta-analysis were used as input for the gene-based genome-wide association analysis (GWGAS). 18,128 protein-coding genes (each containing at least 1 GWAS SNP) from the NCBI 37.3 gene definitions were used as basis for GWGAS in MAGMA25 (see URLs). The Bonferroni-corrected genome-wide significance threshold was .05/18,128 genes=2.76×10-6.