Somogyvári et al. (2012) proposed spike CSD (sCSD) to estimate the CSD after optimizing for the best locations of the sources from the recording electrodes that recreates the spike data (see Figure 13A). The method has been used to analyze recordings from a 16-electrode probe in vivo. Although sCSD has been used to solve for the CSD at the optimized locations of the sources, it assumes that the number of electrodes is equal to the number of sources to solve for. The over-simplification of the number of current sources in sCSD results in errors, especially when the orientation of the neuron being analyzed is at an angle with respect to the measuring electrodes.
