The CSDP is a multi-cohort, within-subject, double-blinded study with repeated, within-subject laboratory assessments of acute responses to alcohol vs. placebo, combined with long-term follow-up of drinking behaviors and AUD symptoms. The study was approved by the University of Chicago Institutional Review Board and participants provided written information consent. The project conducted testing sessions at the Clinical Addictions Research Laboratory at the University of Chicago. Participants undertook initial laboratory sessions from March 2004 to July 2006. They underwent regular follow-up interviews and were invited to participate in identical, double-blinded alcohol and placebo re-examinations five and ten years later (see CONSORT diagram, Suppl. Figure 1).
