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Chunk #20 — RESULTS — Target details pages — Target expression data

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TCRD and Pharos 2021: mining the human proteome for disease biology.
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The target expression data panel has also been expanded, as shown in Figure 6. We replaced the static human figure with an expanded, interactive anatomogram (18). This visualization contains both male and female figures, allowing sex-specific tissue information (e.g., from GTEx) to be highlighted. Users can toggle the brain image separately, for more fine-grained brain tissue expression visualization. All figures are zoomable and pannable, to improve visibility. When possible, all source tissues have been mapped to standardized Uberon (38) identifiers, enabling us to merge repetitive tissues. Expression data can be viewed by source, and tissue values are searchable. Clicking on a tissue panel, like the disease associations section, allows users to view detailed provenance of the data, both showing the source and relevant confidence values for the tissue expression. Gradient coloration allows us to display the tissue expression level, either a qualitative value (low medium, high), or a numeric value scale, depending on the data source, giving users a quick visualization of this data. We note that several sources have an overlap in data and content; however, they may also