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Chunk #19 — RESULTS — Target details pages — Predicted viral interactions

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TCRD and Pharos 2021: mining the human proteome for disease biology.
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Predicted viral-human protein interactions from the P-HIPSTer atlas are displayed in a separate panel that shows a list of viruses and their associated taxonomic data, specifically for the targeted human protein. Each virus also lists the viral proteins that the human protein is predicted to interact with, in addition to a likelihood ratio, which measures the strength of the sequence- and structure-based prediction. These features are shown in Figure 5, using ACE2, the angiotensin converting enzyme 2, as example. ACE2 is the functional entry receptor for both severe acute respiratory syndrome (SARS) coronaviruses, SARS-CoV (36) and SARS-CoV-2 (37).