While PDB identifiers have always been available in Pharos, they were previously displayed as a list of linkouts with no additional information (33). In Pharos 3.0, the PDB section was expanded and redesigned to display three-dimensional (3D) structures for proteins, including bound ligands where available. This 3D visualization, employing NGL Viewer (34,35), is highly interactive, allowing users to drag, zoom, pan and spin the structure to thoroughly examine it. This interface also enables users to browse the PDB identifiers and structures associated with a given target. Clicking on a table row loads the respective PDB entry, and displays the ligands shown in the structure. Other details include the reference source for the id, as well as the method used to generate the structure. This feature is highlighted in Figure 5.
