can be understood as an index of network centrality (for a detailed technical review see, for a detailed technical review see, Jiang & Zuo, 2016). Hence the changes in ReHo of AUD individuals indicate that specific regional neuropopulations are more strongly connected during resting state; these include superior frontal gyrus, medial frontal gyrus, and middle temporal gyrus (Tu, Wang, Liu, & Zheng, 2018). Abstinent alcoholics who completed a detoxification program versus those that withdrew from treatment showed enhanced resting state functional connectivity between striatum and insular cortex, the executive network and the amygdala, and the salience network and the striatum, precuneus, and amygdala. This network hyper-connectivity was directly correlated to the individuals’ craving intensity (Kohno, Dennis, McCready, & Hoffman, 2017). Furthermore, AUD patients that abstained from alcohol for 3 weeks to 10 months had a less efficient connectivity between the left hippocampus and other task-activated networks when viewing emotional faces, while their pallidum was more efficiently connected when viewing alcoholic beverages. Hence longer sobriety may lead to adaptive neural changes shifting connectivity from systems encoding emotional salience towards drug reward, which in turn, may affect the individual’s cognitive control and ability to prevent relapse (Alba-Ferrara, Muller-Oehring, Sullivan, Pfefferbaum, & Schulte,
