Health and Lifestyle Questionnaires were sent to two cohorts of Australian twins and their families (parents, children, spouses and siblings), the first in 1988 and the second in 1990. The total number of participants was over 27,000, with an age range of 17 to 96 (M = 39.7, SD = 15.3). Phenotypic data on the TPQ were available for 20,464 individuals, of which 5117 (1727 males and 3390 females) from 2567 independent families were genotyped. Phenotypic and genotypic data collection was approved by the Queensland Institute of Medical Research (QIMR) Ethics Committee and informed consent was obtained from all participants. More details about the phenotypic data collection can be found elsewhere (Heath, et al., 1994; Keller, et al., 2005).
