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Chunk #11 — Introduction

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A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality.
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In a sample of 5117 Australians of European ancestry from 2567 families, we perform the first GWA study of Cloninger’s temperament scales, in order to identify common genetic variants associated with individual differences in personality. Identification of genetic variants underlying personality traits might also broaden our understanding of behavioural and psychiatric disorders related to personality. On the other hand, if we do not detect any genetic variants that explain a substantial part of the variance in these traits, this would have strong implications regarding the genetic architecture of personality variation and its evolutionary basis.