paperKB
coga / coga-kb
Help
Sign in

Chunk #25 — Results — Integration with functional genomic data

Source
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.
Embedded
yes

Text

We further characterized the AFA signal (rs115539978) using psychophysiology and imaging datasets available through the Grady Trauma Project (GTPC) and found evidence that this lead SNP captures a genomic region that is also associated with increased amygdala volume and fear psychophysiology in a traumatized population (Supplementary Note 1 and Supplementary Fig. 26).