Recently, the ongoing intrinsic activity in the human brain during resting state has attracted considerable attention in neuroscience. The brain resting state is thought to be an energetically costly condition characterized by a rich neural activity and long-range interneuron connections in specific brain circuits (e.g., the default mode network or DMN) that are temporally interrupted or attenuated during performance of sensorimotor or cognitively-demanding tasks [19], [20]. This intrinsic functional organization during rest allows the brain to allocate resources and ready itself for changes in internal and external environments. Therefore, the investigation of functional connectivity during resting state rather than during a particular task may reveal an intrinsic functional disintegration between brain regions in SLPE.
