into the Aroian test. We considered a decrease of the regression coefficients of p < 0.05 significant. Of note, both GMV- and FC-VM/VSM-PLS maximize the correlation between GMV or FC and episodic memory and it is therefore not surprising that both GMV and FC predict episodic memory capacity significantly. However, we are not interested in this correlation per se (as it would be considered double-dipping, see Kriegeskorte et al., 2009) but in the mediating effect of functional connectivity. To test the specificity of the relationship between structural integrity, functional connectivity and episodic memory capacity, we also conducted a mediation analysis using functional connectivity as the independent variable and structural integrity as the mediator variable.
