In the combined CADD and GADD analysis, rs9291283 was nominally associated with AAD in adulthood (p = 0.057; Table IV). Results from the spectral decomposition set the multiple SNP significance threshold required to keep Type I error rate at 5% at 0.019. In this analysis rs9291283 showed a trend toward association with AAD in adulthood at p = 0.057, replicating the trending association between rs9291283 and adult AAD in the CADD sample. However, neither of these associations was statistically significant.
