In the GADD sample, rs9291283 was associated with CD (Table III). Results from spectral decomposition indicated a multiple SNP significance threshold required to keep Type I error rate at 5% is 0.019. In this sample, rs9291283 was significantly associated with CD in adolescence/young adulthood at p = 0.005, a finding that was not seen in the CADD sample. Again, the A allele was shown to be over-transmitted to extreme offspring.
