Rs9291283 was suggestively associated with AAD in adulthood in the CADD sample (Table II). Results from the spectral decomposition to correct for multiple SNP testing indicated the significance threshold required to keep Type I error rate at 5% is 0.017. One should bear in mind an additional correction for the four multiple phenotypes, but since the phenotypes are correlated we present results as comparison to the 0.017 cut-off. Although rs279871 was included in the spectral decomposition and FBAT analysis it was not significantly associated with the phenotypes of interest (results not shown). In this analysis rs9291283 showed a trend toward association with AAD in adulthood at p = 0.063, with the A allele conferring risk to AAD.
