similar levels of ethanol intake and preference based on 3 hours of consumption during the first 2 days of saline injections (denoted as day 2 in all graphs). Ethanol and total fluid intake are presented as g/kg/3 hours. From day 3 in both drinking tests, mice were administered saline or drugs once daily and results are presented as the average from 2-day periods of consecutive drinking using different bottle positions. Overall, mice were exposed to ethanol for at least 3 weeks followed by 4 days of measured drinking before beginning the drug studies, which lasted up to 12 days. Our definition of chronic drinking is thus based on at least 5 weeks of ethanol exposure.
