Chunk #42 — Materials and Methods — Prediction of S-Palmitoylation Sites and Nuclear Localization Signals

Source

Potential Role of S-Palmitoylation in Cancer Stem Cells of Lung Adenocarcinoma.

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We predicted the ZDHHCs nuclear localization signals (NLSs) specific to the importin αβ pathway by cNLS Mapper, based on the amino acid sequence of each protein. cNLS Mapper extracted the putative NLS sequences with a score equal to or more than the selected cut-off score. Higher scores indicated stronger NLS activities.