The PPI network was retrieved from STRING v.11.0.6 The minimum required interaction score was set at medium confidence (0.400). Active interaction sources included text-mining, experiments, databases, co-expression, neighborhood, gene fusion, and co-occurrence. Only individual networks with 10 or more nodes were included for further analysis. Disconnected nodes were hidden in the network. The edges indicated both functional and physical protein associations. Each node represented an input protein, and the line thickness indicated the strength of data support.
