to assess the proportion of affected relatives (Turner et al., 1993, Stoltenberg et al., 1998, Milne et al., 2008) or to parse out genetic influences from family environment effects (Light et al., 1996, Zucker et al., 1994). Most family method studies for AUD (Roy et al., 1994, Roy et al., 1996, Rice et al., 1995) show high specificity (correct indication of negative diagnosis) and moderate sensitivity (correct indication of positive diagnosis), but also acknowledge the potential for reporting bias based on the sex and age of both the informant and the subject, as well as the closeness of the relationship between the subject and informant. Future studies with more detailed FH measures would be informative in this regard. Finally, although we tested whether FH was associated with the social control indicators and did not find evidence for gene-environment correlation,8 twin and adoption studies and longitudinal studies are better-suited to testing neighborhood selection effects.
