Our study used data from a large, nationally-representative sample of adult drinkers to examine associations of FH of alcohol problems with two different alcohol outcomes along the risk continuum. The large sample also permitted us to examine differences by sex and by race/ethnicity. These strengths are somewhat offset by a few limitations. First, despite the large sample, we may have had limited power to test some interactions in the stratified models. Further, based on available survey measures, we used DSM-IV criteria for alcohol dependence, so our findings bear replication using DSM-5 criteria. With a large enough sample, this would allow distinction of risk factors for mild, moderate and severe AUD. Additionally, our measure of FH considered the presence of affected relatives across multiple generations (Dawson et al., 1992, Hill et al., 1994, Kendler et al., 2018); however, we were unable to assess the proportion of affected relatives (Turner et al., 1993, Stoltenberg et al., 1998, Milne et al., 2008) or to parse out genetic influences from family environment effects (Light et al., 1996, Zucker et al., 1994). Most family method
