The columns of result tables can be configured for customized downloads in tab-delimited or Excel format. All data is available in RDF (http://www.w3.org/RDF/), a W3C standard for publishing data on the Semantic Web. All search results can be retrieved as RSS feeds for integration with external tools such as news feed readers or Yahoo Pipes. Programmatic access to data and search results is possible via simple HTTP (REST) requests (http://www.uniprot.org/help/technical). Java applications can also make use of our Java API (UniProtJAPI) (18).