In examining the clinical significance of the weakness and anxiety/depression cannabis withdrawal symptoms, distress/impairment showed a strong and statistically significant relationship to the symptom count for both types of withdrawal symptoms in the full sample of frequent cannabis users (Table 4) and the subsample (Table 5). Furthermore, a strong, significant relationship was found between use of a substance to relieve/reduce cannabis withdrawal and both the weakness and anxiety/depression withdrawal symptoms in the full sample of frequent cannabis users (Table 4) and the subsample (Table 5).
