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Chunk #33 — Results — 3. Individual SNPs effects on Subjective Responses to Alcohol — 3. A. Visual Analog Drug Effect Questionnaire (VAS)

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GABRA2 markers moderate the subjective effects of alcohol.
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p=0.0045). rs279826: Negative effects score was lower in carriers of the minor allele, G, than in subjects homozygous for the common allele (F(1, 61) = 8.80, p=0.0043). rs279828: Negative effects score was lower in carriers of the minor allele, C, than in subjects homozygous for the common allele (F(1, 63) = 9.07, p=0.0037). rs 279836: Negative effects score was lower in carriers of the minor allele, A, than in subjects homozygous for the common allele (F(1, 62) = 8.08, p=0.0061) (Figure 3.B.). When the SNPs described above were analyzed in the Caucasian subsample only, the effects were similar (Table 3).