Ethanol sensitivity and acute functional tolerance in C. elegans with mutations in Clic orthologues(A) Effect of ethanol exposure on relative locomotor speed (percent of untreated animals) in N2 control (open circles) and Clic mutants (exl-1(ok857), light grey squares; exc-4(rh133), dark grey triangles; exc-4(rh133);exl-1(ok857), black diamonds). Data are from 4 independent experiments where 10 worms per genotype contributed to an average speed for a population. (B) Internal ethanol concentrations in N2 control and Clic mutants were determined as described in Materials and Methods
