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Chunk #30 — Methods — Animals

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The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents.
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Pdgfra-CreER and Sox10-CreER mice were generously provided by Dr. William D. Richardson (Wolfson Institute for Biomedical Research, University College London, London, UK). Cnp-Cre (generated by Dr. Klaus Nave), Olig2Flox/Fox and Sox11Flox/Flox mice were generously provided by Dr. Luis F. Parada (Department of Developmental Biology, University of Texas Southwestern Medical School, Dallas, TX, USA). NG2-Cre and Olig1-Cre mice were from Jackson Laboratory (stock number: 008533 and 011105). Setdb1Flox/Flox mice were generously provided by Dr. Yan Jiang (Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and MOE Frontier Center for Brain Science, Fudan University, 200032, Shanghai, China).