subjects from high-risk families, which are not well represented in existing longitudinal investigations; b) targeting not only alcohol consumption, symptoms, and treatment, but a variety of other alcohol-relevant outcomes, such as depression and impaired cognitive functioning; and c) identifying young adult predictors of later life drinking that encompass environmental, behavioral, psychiatric, genetic, neurophysiological (EEG/ERP), and neuropsychological information, thereby allowing predictive models to incorporate a broad spectrum of explanatory variables.