The replication of the CTF's factor structure from the CT Study, a population‐based twin and family sample screened for trauma exposure, in the CAT Study, a case–control study of opioid dependence, is a major strength of the current report. This replication, coupled with the demonstration that applying factor loadings from the CT Study to OZ‐ALC GWAS data yield extremely similar estimates of association, support the likely utility of the CTF in a variety of samples. However, whether this factorial architecture and distribution of scores can be recovered in general population samples with putatively lower exposure to trauma should be explored. Furthermore, similar results were obtained based on telephone and face‐to‐face interviews. The detailed trauma assessments conducted in the three samples contribute to the robustness of the CTF.
