Chunk #31 — Results — Overall ability to detect eQTLs depends on tissue type and gene expression

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Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.

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We performed independent analyses of probes that were only detected in one tissue as more probes were tested in brain (1877 in frontal cortex and 1853 in cerebellum) than in blood (413). There were 107 significant associations in cerebellum and 90 in frontal cortex compared to 21 in blood but we did not find over-representation of traits annotated as brain related in the brain datasets (Table 2).