Case definitions were always based on clinical descriptions related to ICD coding schemes and the case definitions in the GBD 2005 operations manual (http://www.globalburden.org/gbdops.html) except for some outcomes (injury, for example) where articles may not have included ICD-10 codes and instead relied on other diagnoses or descriptions which can be coordinated with the codes. Uncorroborated self-reports were excluded.
