for immune response) for the hippocampus (Supplementary Fig. 7b and Supplementary Data 4). Although the caudate nucleus and DLPFC showed modules enriched for the immune response for both directions of effect, the most significantly enriched non-gray module (two-sided Fisher’s exact test) was associated with a specific direction of effect consistent with differential expression analysis for the caudate nucleus (cyan module, DEGs upregulated in African ancestry) and DLPFC (pink module, DEGs downregulated in African ancestry).
