Among the 276 genes that differed between the ethanol and water groups in the ACB-shell, 36 genes were located within rat ethanol preference QTLs (Table 1; also see Supplemental Table B). The highest localization of genes occurred in rat ethanol preference QTL Alc 4 on rat chromosome 5 (11 genes) and QTL Alc17 on rat chromosome 6 (10 genes). There were 7 genes located in both a rat and a mouse ethanol QTL, i.e., Rab14, Ptgs1, Nudc, Fabp3, Ncdn, Fbxo2, and Nrgn. Five (Rab14, Ptgs1, Ncdn, Fbxo2, Nrgn) of these 7 genes were listed within a significant GO BP category, i.e., ‘synaptic transmission’ and ‘neurite development’.
