Ingenuity® pathways analysis indicated several different networks were altered by ethanol drinking (Table 3). One network involved in transcription had 24 genes up-regulated and only 5 down-regulated in the ethanol group compared to the water control group. Similar differences in up-regulated versus down-regulated genes were observed for other networks, e.g., Wnt/beta-catenin signaling, glucocorticoid receptor signaling, NFKB signaling, and long-term potentiation (Table 3).