a low LR reported a greater reduction in drinking quantities when enrolled in the program tailored to address low LR than in the standard prevention program. A larger replication (N=500) at the same university found similar LR by program interactions in reducing drinking quantity (Schuckit et al., 2015). This suggests that tailoring prevention programming to an individual’s biologically predisposed low LR may be more effective than standard one-size-fits-all programs in reducing risky drinking among college students.