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Chunk #58 — Systematic review of fMRI studies — Transition into alcohol use

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The effect of alcohol consumption on the adolescent brain: A systematic review of MRI and fMRI studies of alcohol-using youth.
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Wetherill, Castro, et al. (2013). This longitudinal study involved 60 participants ages 12–14 years who displayed minimal, if any, alcohol use at baseline, and who were then followed up and retrospectively classified as future AU (defined as heavy drinkers who experience alcohol-induced blackouts, B+; n = 20; 9 females, future heavy drinkers who do not experience alcohol-induced blackouts, B−; n = 20; 9 females) and non-AU youth (continuous non-drinkers, n = 20; 9 females). At baseline, participants carried out the same go/no-go task as reported in Norman et al. (2011) and Wetherill, Squeglia, Yang, & Tapert (2013). Despite no group differences in performance, AU youth showed significant differences in several brain regions.