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Chunk #17 — 2. Methods — 2.1. Sample and Measures

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Association of Polygenic Liability for Alcohol Dependence and EEG Connectivity in Adolescence and Young Adulthood.
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between 0.02 Hz to 100 Hz and recorded using the Neuroscan software system (Compumedics Limited; El Paso, TX, USA) running on i86 PCs. EEG procedures were identical at all collection sites. Further details regarding the EEG coherence data processing is provided in the Supplemental Material. Bipolar electrode pairs were derived to reduce volume conduction effects [11], and the 27 coherence pairs used in this study (depicted in Figure 1) were selected based on a previous study of EEG coherence [24]. Conventional Fourier transform methods [11] were used to calculate coherence. Coherence measures were generated at the following frequencies: low theta (3–5 Hz), high theta (5.5–7 Hz), low alpha (7.5–9 Hz), high alpha (9.5–12 Hz), low beta (12.5–16 Hz), mid beta (16.5–20 Hz), and high beta (20.5–28 Hz) and between pairs of bipolar derivations as described in Figure 1.