To test the performance of MAGENTA on traits whose underlying biology has been well studied, we analyzed three GWA study meta-analyses of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglyceride blood levels [34]. All three meta-analyses were performed with 19,840 individuals from seven GWA studies, on 2,552,754, 2,552,580 and 2,552,773 genotyped and imputed SNPs for the LDL cholesterol, HDL cholesterol and triglyceride meta-analyses, respectively.