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Chunk #47 — Materials and Methods — GWA studies and meta-analyses analyzed

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Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits.
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To test the performance of MAGENTA on traits whose underlying biology has been well studied, we analyzed three GWA study meta-analyses of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglyceride blood levels [34]. All three meta-analyses were performed with 19,840 individuals from seven GWA studies, on 2,552,754, 2,552,580 and 2,552,773 genotyped and imputed SNPs for the LDL cholesterol, HDL cholesterol and triglyceride meta-analyses, respectively.