Genotyping results were entirely consistent for 1119 participants: for 671, no minor alleles were detected at any successfully genotyped locus (H2 haplotype absent); for 448, a minor allele was detected at each locus (H2 haplotype present). For another 9 individuals, genotyping results included minor inconsistencies that primarily involved the more difficult to genotype rs3029044 insertion/deletion: 6 who were homozygous for the major allele at all but one successfully genotyped locus were coded as H2 haplotype absent; 3 others who were homozygous for the major allele at a single locus (with minor alleles present at the other successfully genotyped loci) were coded as H2 haplotype present. Finally, 3 individuals who had intermediate genotypic results were coded as indeterminate for H2 haplotype and excluded from subsequent analyses. Haplotypes were similarly assigned for all additional family members (including parents) with genotypic data available and Pedcheck (O’Connell & Weeks, 1998) was used to look for Mendelian errors (total N=1814). No Mendelian errors in haplotype assignment were identified. The final sample (N=1128 individuals from 476 families) consisting of all those with data available for H2
